Associate Principal Scientist, Systems Biology Toxicologist

Job Description

The Non-Clinical Drug Safety (NDS) organization of our company's Research Laboratories is currently seeking a Systems Biology Toxicologist lead within Investigative Toxicology at the West Point, PA site. 

This scientific leadership role will drive the development, strategic alignment, and application of cutting-edge genomics assays and systems biology analytics towards the identification and mechanistic de-risking of program liabilities.  This includes identifying new opportunities in genomics, systems biology and/or analytics, collaborating with laboratory scientists and analysts for development and implementation, communicating utilization strategy to leadership and program teams, and applying the approaches towards pipeline programs. It also includes working closely with program development teams to understand potential program liabilities, applying Systems Toxicology resources to assist risk assessment/mitigation, and overseeing the interpretation and communication of program-related Systems Toxicology data. The lead will actively participate in ongoing and future academic/industry/regulatory partnerships to advance the usage and regulatory acceptance of systems toxicology approaches, biomarkers and analytics as well as spearhead both internal and peer-reviewed publications and presentations.

Education:

• Ph.D. or MD/Ph.D. (with 4+ years), Master's (with 8+ years) or Bachelor's (with 12+ years) in toxicology, genetics/genomics, bioinformatics or related discipline and relevant industry experience

Required Experience and Skills:

• Prior experience in toxicology and/or program development
• Prior experience with modern genomics (eg single cell and spatial sequencing)
• Prior experience in systems biology analysis
• Passion for development of novel technologies and application to drug development
• Strong communication, collaboration, and leadership skills including ability to distill and communicate complex biological and analytical concepts to scientists from diverse disciplines

Preferred Experience and Skills:

• AI/ML-based analytics
• Mathematical programing (eg R, Python, Matlab)

#EligibleforERP 

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders).  Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace.  All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics.  For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.  This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

Domestic/International

VISA Sponsorship:

Yes

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

1st - Day

Valid Driving License:

No

Hazardous Material(s):

No

Job Posting End Date:

07/31/2024

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.