CFD Engineer

We create a place where people can grow, be their best, be safe, and feel welcome, valued, and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK

The Modeller will work cross-modality, integrated directly on projects, to deliver advanced modeling approaches to accelerate development, increase fundamental understanding, improve risk assessment and deliver more robust processes, products and regulatory filings. This includes the application of mechanistic, data driven and hybrid modelling in process design, control strategy identification and advanced process monitoring & control for Drug Product processes. 

In this role, YOU will..

• Use mechanistic, data driven and hybrid modelling to efficiently deliver priority team objectives including but not limited to process design, quantitative risk assessment, identification of Critical Process Parameters, design space definition, and implementation of advanced model based process monitoring and controls.

• Use engineering, chemical or materials science knowledge to postulate mechanisms for physiochemical processes and develop or modify existing mathematical models to describes those mechanisms. 

• Translate mathematical models to computer models using software platforms (e.g. gPROMS, Aspen, ANSYS Fluent) or by writing custom programs (Using Matlab, Python, C++ etc.)

• Develop and maintain key system modeling platforms.  Leverage external expertise and funding through pre-competitive alliances (e.g. System based Pharmaceutics)

• Work closely with the QbD, Regulatory and other experts to integrate modeling (Simulation) into QbD process development.

• Work closely with Statistical Sciences to develop the best in-silico experimental design and to engage them to assess model uncertainty and model predictive confidence limits.

• Stay current with new modeling techniques through publications, conferences and academic and precompetitive collaborations

• Advocate and comply with GMP requirements for recording experiments and associated data and writing modeling sports including scientific review and data checking.

Basic Qualifications:

• M.S. or PhD in Chemical Engineering/ Physical Chemistry or equivalent experience with an emphasis on development and implementation of mechanistic mathematical models

• Ability to translate mathematical models into computer programs using Matlab, Python or similar software tools.

• An understanding of statistical science and related software tools that enable sound experimental design and interpretation of models.

• Experience with CFD software such as ANSYS FLUENT, OPENFOAM, STAR-CCM+ or flow sheet modelling software such as Aspen or gPROMS.

• Understands and complies with GMP requirements including; data integrity and model validation / maintenance.

• English proficiency (written and spoken)

Preferred Qualifications:

• Good interpersonal, organizational and communications skills

• Ability to multi-task and manage workload independently.

• Ability to work within a team and communicate effectively

#Hybrid

Closing Date for Applications – July 9th, 2024

Please take a copy of the Job Description, as this will not be available post closure of the advert. 
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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